Objective: To investigate the effects of chemical substances contained in agarwood on the body's inflammatory response, oxidative stress, oral and intestinal micro-ecology, as well as their role in various mucosal diseases, such as recurrent aphthous ulcer (RAU) and inflammatory bowel disease (IBD). Materials and Methods: By reviewing and summarizing literature from the past decade on agarwood and its related chemical components composition, as well as their effects on RAU and IBD, we explore the role of agarwood in the body and its relationship with mucosal-related diseases. Results: The Specific components in agarwood, such as sesquiterpenes, flavonoids, etc., can regulate the body's inflammatory response and oxidative stress levels through various signaling pathways, thereby affecting the mucosal status of the oral and intestinal cavity, such as influencing the expression of tight junction proteins between epithelial cells to restore mucosal barrier permeability. Conclusion: Agarwood can down-regulate the inflammatory response by inhibiting various signaling pathways, mainly NF-κB, reduce oxidative stress by decreasing ROS expression, improve the mucosal barrier in the oral and intestinal cavity, and simultaneously impact the improvement of oral and intestinal micro-ecology. It plays a certain controlling role in mucosal-damaged diseases such as IBD and RAU, laying the foundation for the transformation, development, and upgrading of the agarwood industry.
| Published in | International Journal of Gastroenterology (Volume 7, Issue 2) |
| DOI | 10.11648/j.ijg.20230702.12 |
| Page(s) | 49-53 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
Agarwood, Anti-Inflammatory, Flavonoids
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APA Style
Yi-Nan Zhang, Zi-Lin Wang, Xiang Guo, Xue-Jing Lin, Hao-Yi Duan, et al. (2023). Empirical Research on the Anti-Inflammatory, Antibacterial, and Mucosal Protective Effects of Agarwood Based on the Oral and Intestinal Microenvironment. International Journal of Gastroenterology, 7(2), 49-53. https://doi.org/10.11648/j.ijg.20230702.12
ACS Style
Yi-Nan Zhang; Zi-Lin Wang; Xiang Guo; Xue-Jing Lin; Hao-Yi Duan, et al. Empirical Research on the Anti-Inflammatory, Antibacterial, and Mucosal Protective Effects of Agarwood Based on the Oral and Intestinal Microenvironment. Int. J. Gastroenterol. 2023, 7(2), 49-53. doi: 10.11648/j.ijg.20230702.12
AMA Style
Yi-Nan Zhang, Zi-Lin Wang, Xiang Guo, Xue-Jing Lin, Hao-Yi Duan, et al. Empirical Research on the Anti-Inflammatory, Antibacterial, and Mucosal Protective Effects of Agarwood Based on the Oral and Intestinal Microenvironment. Int J Gastroenterol. 2023;7(2):49-53. doi: 10.11648/j.ijg.20230702.12
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Download@article{10.11648/j.ijg.20230702.12,
author = {Yi-Nan Zhang and Zi-Lin Wang and Xiang Guo and Xue-Jing Lin and Hao-Yi Duan and Nan Wang and Shui-Chang Zhang and Wei-Ru Cheng and Fan-Di Xu and Minhaj Ahmad and Zhu-Ling Guo},
title = {Empirical Research on the Anti-Inflammatory, Antibacterial, and Mucosal Protective Effects of Agarwood Based on the Oral and Intestinal Microenvironment},
journal = {International Journal of Gastroenterology},
volume = {7},
number = {2},
pages = {49-53},
doi = {10.11648/j.ijg.20230702.12},
url = {https://doi.org/10.11648/j.ijg.20230702.12},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijg.20230702.12},
abstract = {Objective: To investigate the effects of chemical substances contained in agarwood on the body's inflammatory response, oxidative stress, oral and intestinal micro-ecology, as well as their role in various mucosal diseases, such as recurrent aphthous ulcer (RAU) and inflammatory bowel disease (IBD). Materials and Methods: By reviewing and summarizing literature from the past decade on agarwood and its related chemical components composition, as well as their effects on RAU and IBD, we explore the role of agarwood in the body and its relationship with mucosal-related diseases. Results: The Specific components in agarwood, such as sesquiterpenes, flavonoids, etc., can regulate the body's inflammatory response and oxidative stress levels through various signaling pathways, thereby affecting the mucosal status of the oral and intestinal cavity, such as influencing the expression of tight junction proteins between epithelial cells to restore mucosal barrier permeability. Conclusion: Agarwood can down-regulate the inflammatory response by inhibiting various signaling pathways, mainly NF-κB, reduce oxidative stress by decreasing ROS expression, improve the mucosal barrier in the oral and intestinal cavity, and simultaneously impact the improvement of oral and intestinal micro-ecology. It plays a certain controlling role in mucosal-damaged diseases such as IBD and RAU, laying the foundation for the transformation, development, and upgrading of the agarwood industry.},
year = {2023}
}
TY - JOUR T1 - Empirical Research on the Anti-Inflammatory, Antibacterial, and Mucosal Protective Effects of Agarwood Based on the Oral and Intestinal Microenvironment AU - Yi-Nan Zhang AU - Zi-Lin Wang AU - Xiang Guo AU - Xue-Jing Lin AU - Hao-Yi Duan AU - Nan Wang AU - Shui-Chang Zhang AU - Wei-Ru Cheng AU - Fan-Di Xu AU - Minhaj Ahmad AU - Zhu-Ling Guo Y1 - 2023/08/10 PY - 2023 N1 - https://doi.org/10.11648/j.ijg.20230702.12 DO - 10.11648/j.ijg.20230702.12 T2 - International Journal of Gastroenterology JF - International Journal of Gastroenterology JO - International Journal of Gastroenterology SP - 49 EP - 53 PB - Science Publishing Group SN - 2640-169X UR - https://doi.org/10.11648/j.ijg.20230702.12 AB - Objective: To investigate the effects of chemical substances contained in agarwood on the body's inflammatory response, oxidative stress, oral and intestinal micro-ecology, as well as their role in various mucosal diseases, such as recurrent aphthous ulcer (RAU) and inflammatory bowel disease (IBD). Materials and Methods: By reviewing and summarizing literature from the past decade on agarwood and its related chemical components composition, as well as their effects on RAU and IBD, we explore the role of agarwood in the body and its relationship with mucosal-related diseases. Results: The Specific components in agarwood, such as sesquiterpenes, flavonoids, etc., can regulate the body's inflammatory response and oxidative stress levels through various signaling pathways, thereby affecting the mucosal status of the oral and intestinal cavity, such as influencing the expression of tight junction proteins between epithelial cells to restore mucosal barrier permeability. Conclusion: Agarwood can down-regulate the inflammatory response by inhibiting various signaling pathways, mainly NF-κB, reduce oxidative stress by decreasing ROS expression, improve the mucosal barrier in the oral and intestinal cavity, and simultaneously impact the improvement of oral and intestinal micro-ecology. It plays a certain controlling role in mucosal-damaged diseases such as IBD and RAU, laying the foundation for the transformation, development, and upgrading of the agarwood industry. VL - 7 IS - 2 ER -
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